So it turns out you can injure your sciatic nerve with PIO shots! The photo shows the "safe" area. The nurse showed Ivan how to find the safe spot...something about the hand and the thumb being placed on the back of the pelvic bone. He is a pro at it it but I still emailed this photo to him as a gentle reminder! Go here to read more.
PIO's are are much more bearable if you stand. I learned this when a doctor at China Camp (fellow China Mom) did my shot for me b/c Ivan could not be there. She told me afterward that PIO's are often less painful if you stand with you toes pointed slightly inward which could also be implemented if you prefer to lie down.